“Evidence suggests that DTP vaccine may kill more children from other causes than it saves from diphtheria, tetanus or pertussis.”


A nurse gives a measles vaccination to a child in Guinea-Bissau. Photo: UNICEF/Roger Lemoyne


Study: DTP Vaccine Associated With 212% Increased Infant Mortality Risk

Posted on: Wednesday, March 15th 2017 at 12:15 pm Written By: Jefferey Jaxen

Study: DTP Vaccine Associated With Increased Infant Mortality.

A study from West Africa’s Guinea-Bissau discovered that all-cause infant mortality more than doubled after the introduction of the DTP vaccination.

(Follow the above link to read more.)

Here is the study referred to in Jeffrey Jaxen’s article.

The Introduction of Diphtheria-Tetanus-Pertussis and Oral Polio Vaccine
Among Young Infants in an Urban African Community: A
Natural Experiment
Available online 1 February 2017Abstract

We examined the introduction of diphtheria-tetanus-pertussis (DTP) and oral polio vaccine (OPV) in an urban community in Guinea-Bissau in the early 1980s.

What I consider to be the important points….

  • In this natural experiment vaccinated children had 5-fold higher mortality than not-yet-DTP-vaccinated children. DTP-only vaccinations were associated with higher mortality than DTP + OPV vaccinations. Hence, DTP may be associated with a negative effect on child survival.
  • Except for the measles vaccines, surprisingly few studies examined the introduction of vaccines and their impact on child survival.
  • DTP was associated with 5-fold higher mortality than being unvacci-
    nated. No prospective study has shown beneficial survival effects of
    DTP. Unfortunately, DTP is the most widely used vaccine, and the pro-
    portion who receives DTP3 is used globally as an indicator of the perfor-
    mance of national vaccination programs.
  • All currently available evidence suggests that DTP vaccine may kill more children from other causes than it saves from diphtheria, tetanus or pertussis. Though a vaccine protects children against the target disease it may simultaneously increase susceptibility to unrelated infections.

Smallpox in the USA


Was smallpox eliminated in the USA by vaccines?

(emphasis mine)

The CDC on smallpox vaccination (USA) in the early 20th century.

Smallpox. Smallpox is the only disease that has been eradicated. During 1900-1904, an average of 48,164 cases and 1528 deaths caused by both the severe (variola major) and milder (variola minor) forms of smallpox were reported each year in the United States (1). The pattern in the decline of smallpox was sporadic. Outbreaks of variola major occurred periodically in the first quarter of the 1900s and then ceased abruptly in 1929. Outbreaks of variola minor declined in the 1940s, and the last case in the United States was reported in 1949.

Source – Achievements in Public Health, 1900-1999 Impact of Vaccines Universally Recommended for Children — United States, 1990-1998

Plotkin and Orenstein on smallpox vaccination (USA)in the early 20th century.

However, antivaccinationist sentiment and antipathy toward compulsory measures prevailed in many states, most of which passed no legislation or prohibited compulsory vaccination. Reported cases of smallpox declined from 102,791 in 1921 to 30,151 in 1931, and between 1932 and 1939, 5000 to 15,000 cases were reported annually, with 23 to 52 deaths. During the following decade, reported cases steadily diminished, the last occurring in 1949. This progress occurred in the absence of any nationally coordinated smallpox control effort, and little is known about the extent of vaccination immunity in the country during the 1940s or about the epidemiology of smallpox. However, improved smallpox control, and eventually its elimination, is attributed by Leak (see below) to the wider availability of better refrigeration and, consequently, better preservation of the vaccine. Routine vaccination continued in the United States until 1971 as a protection in case smallpox was imported and was enforced in most states by compelling vaccination as a requirement for school entry.

Vaccines. 3rd edition. Editors – S.A. Plotkin and W.A. Orenstein. Published 1999.

J.P. Leak, Surgeon Public Health Rep. 1927 Jan 28; 42(4): 221–282.

Who are Plotkin and Orenstein?

Stanley Plotkin 

Dr. Stanley Plotkin has such a storied vaccine development career that one might say he wrote the book on vaccines. In fact, he did and his book “Vaccines”, now in its 6th edition, is the standard medical reference. Dr. Plotkin’s background reads like a roadmap of 20th century infectious disease—polio, rubella, rotavirus, rabies, and varicella (chicken pox). His career has been spent on the development of these vaccines and he now advises and influences clinical practice, academia, vaccine policy, as well as industry.

Walter Orenstein

Dr. Orenstein worked for 26 years in the Immunization Program at the Centers for Disease Control and Prevention. From 1988-2004, he was the Director of the United States Immunization Program. Dr Orenstein is a Professor of Medicine, Epidemiology, Global Health, and Pediatrics, as well as Associate Director of the Emory Vaccine Center and Director of the Emory Program on Vaccine Policy and Development

The Eradication of Polio

A well written and researched article. Definitely worth a read.

Polio. We can’t just all stop vaccinating, because, well… polio. Right? This is the undying retort of everyone who questions the anti-vaccine stance. I get it. No one wants polio to “come back”. Not even the anti-vaxxers. But, was it ever truly eradicated? I know, I sound nuts. Let’s back up. In the 50s, prior to the introduction […]

via The Eradication of Polio. — a evidence-based, heartfelt blog.