Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community

Jing Yan, Michael Grantham, Jovan Pantelic, P. Jacob Bueno de Mesquita, Barbara Albert, Fengjie Liu, Sheryl Ehrman, Donald K. Milton and EMIT Consortium

PNAS 2018; published ahead of print January 18, 2018, https://doi.org/10.1073/pnas.1716561115

Edited by Peter Palese, Icahn School of Medicine at Mount Sinai, New York, NY, and approved December 15, 2017 (received for review September 19, 2017)

 

Article Figures & SI Authors & Info  PDF

Significance

Lack of human data on influenza virus aerosol shedding fuels debate over the importance of airborne transmission. We provide overwhelming evidence that humans generate infectious aerosols and quantitative data to improve mathematical models of transmission and public health interventions. We show that sneezing is rare and not important for—and that coughing is not required for—influenza virus aerosolization. Our findings, that upper and lower airway infection are independent and that fine-particle exhaled aerosols reflect infection in the lung, opened a pathway for a deeper understanding of the human biology of influenza infection and transmission. Our observation of an association between repeated vaccination and increased viral aerosol generation demonstrated the power of our method, but needs confirmation.

(emphasis mine)

Go here for plain language story- Flu Vaccine Increases Your Risk of Infecting Others by 6-Fold, Study Suggests

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The Eradication of Polio

A well written and researched article. Definitely worth a read.

Polio. We can’t just all stop vaccinating, because, well… polio. Right? This is the undying retort of everyone who questions the anti-vaccine stance. I get it. No one wants polio to “come back”. Not even the anti-vaxxers. But, was it ever truly eradicated? I know, I sound nuts. Let’s back up. In the 50s, prior to the introduction […]

via The Eradication of Polio. — a evidence-based, heartfelt blog.