“Evidence suggests that DTP vaccine may kill more children from other causes than it saves from diphtheria, tetanus or pertussis.”

A nurse gives a measles vaccination to a child in Guinea-Bissau. Photo: UNICEF/Roger Lemoyne

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Study: DTP Vaccine Associated With 212% Increased Infant Mortality Risk

Posted on: Wednesday, March 15th 2017 at 12:15 pm Written By: Jefferey Jaxen

Study: DTP Vaccine Associated With Increased Infant Mortality.

A study from West Africa’s Guinea-Bissau discovered that all-cause infant mortality more than doubled after the introduction of the DTP vaccination.

(Follow the above link to read more.)

Here is the study referred to in Jeffrey Jaxen’s article.

The Introduction of Diphtheria-Tetanus-Pertussis and Oral Polio Vaccine
Among Young Infants in an Urban African Community: A
Natural Experiment
Available online 1 February 2017Abstract

Background
We examined the introduction of diphtheria-tetanus-pertussis (DTP) and oral polio vaccine (OPV) in an urban community in Guinea-Bissau in the early 1980s.

What I consider to be the important points….

• In this natural experiment vaccinated children had 5-fold higher mortality than not-yet-DTP-vaccinated children. DTP-only vaccinations were associated with higher mortality than DTP + OPV vaccinations. Hence, DTP may be associated with a negative effect on child survival.
• Except for the measles vaccines, surprisingly few studies examined the introduction of vaccines and their impact on child survival.
• DTP was associated with 5-fold higher mortality than being unvacci-
  nated. No prospective study has shown beneficial survival effects of
  DTP. Unfortunately, DTP is the most widely used vaccine, and the pro-
  portion who receives DTP3 is used globally as an indicator of the perfor-
  mance of national vaccination programs.
• All currently available evidence suggests that DTP vaccine may kill more children from other causes than it saves from diphtheria, tetanus or pertussis. Though a vaccine protects children against the target disease it may simultaneously increase susceptibility to unrelated infections.

Vital Statistics graphs

All graphs sourced from –

VITAL STATISTICS RATES IN THE UNITED STATES

1940-1960

By Robert  D.  Grove,  Ph.  D.and Alice  M.    Hetzel

U.S.  DEPARTMENT OF  HEALTH, EDUCATION, AND WELFARE PUBLIC HEALTH SERVICE

Washington,   D.C.   1968

National   Center  for Health  Statistics

Click to access vsrates1940_60.pdf

Note – Graphs show death rates for diseases, preceded by the approximate date when vaccination for disease was widely instituted.

Diphtheria

Immunization for Diphtheria was incorporated with tetanus toxoid and pertussis vaccine and became routinely used in the 1940s.

Reference:  http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/dip.pdf

CDC on TB vaccination

Tuberculosis

BCG vaccination is not recommended as a routine strategy for TB control,

References: http://www.cdc.gov/mmwr/preview/mmwrhtml/00041047.htm

TB Vaccine (BCG)

Bacille Calmette-Guérin (BCG) is a vaccine for tuberculosis (TB) disease. This vaccine is not widely used in the United States, but it is often given to infants and small children in other countries where TB is common. BCG does not always protect people from getting TB. (emphasis mine)

References: http://www.cdc.gov/tb/topic/vaccines/

Typhoid

Immun Infekt. 1983 Jan;11(1):16-22.

[Typhoid vaccination yesterday and today].

Abstract

Despite the early attempts to produce resistance against typhoid fever with parenteral vaccination by Pfeiffer and Kolle in 1896, and with oral vaccines by Carroll in 1904, it was not until the 1950s when typhoid vaccine efficacy was prospectively evaluated in both well-controlled field trials and human volunteer studies. Among the parenteral whole cell preparations the acetone-inactivated and heat-phenol-killed vaccines, respectively, demonstrating an efficacy of 60-90% for 3-5 years, have received most attention. Oral killed typhoid vaccines have enjoyed popularity for many years, but their effectiveness has never been proven under statistically and epidemiologically controlled conditions

Reference: http://www.ncbi.nlm.nih.gov/pubmed/6341210

Measles

Measles vaccine introduced 1963

Achievements in Public Health, 1900-1999 Impact of Vaccines Universally Recommended for Children — United States, 1990-1998

Reference: http://www.cdc.gov/mmwr/preview/mmwrhtml/00056803.htm

Note – Measles vaccines were introduced in 1963 but coverage was low until the 1970’s.

1966-1970 Measles vaccine coverage among 1- to 4-year-old children did not exceed 63% for any year.

Reference: http://jid.oxfordjournals.org/content/189/Supplement_1/S17.long

Dysentery

No vaccine available

Note- decline parallels that of other infectious diseases, suggesting that other factors were responsible for fall in death rates.